Papers

2021

  • Se-Na Kim, Chun Gwon Park, Chang Hee Min, Seung Ho Lee, Yun Yong Lee, Na Kyeong Lee, and Young Bin Choy*, Shape-dependent intracellular uptake of metal-organic framework nanoparticles, J. Ind. Eng. Chem. Accepted

These authors contributed equally as co-first author to this work.

  • Hee seung Seo, Chi-Pin James Wang, Wooram Park and Chun Gwon Park*, Short Review on Advances in Hydrogel-based Drug Delivery Strategies for Cancer Immunotherapy, Tissue Eng Regen Med, Accepted

These authors contributed equally to this work.

  • Na Kyeong Lee, Chi-Pin James Wang, Jaesung Lim, Wooram Park, Ho-Keun Kwon, Se-Na Kim, Tae Hyung Kim and Chun Gwon Park*, Impact of the conjugation of antibodies to the surfaces of polymer nanoparticles on the immune cell targeting abilities, Nano Converg. 2021 Aug 16;8(1):24.
  • Jaesung Lim1, Yun Young Lee1, Young Bin Choy, Wooram Park and Chun Gwon Park*, Sepsis diagnosis and treatment using nanomaterials, Biomed Eng Lett. 2021 Jul 12;11(3):1-14.

1 These authors contributed equally to this work.

  • Jihye Hong, Mikyung Kang, Mungyo Jung, Yun Young Lee, Yongbum Cho, Cheesue Kim, Seuk Young Song, Chun Gwon Park, Junsang Doh* and Byung-Soo Kim*, T Cell-derived Nanovesicles for Cancer Immunotherapy, Adv Mater. 2021 Jul 8;e2101110.
  • Jun Yong Kim, Won-Kyu Rhim, Hyo Jeong Seo, Joo Youn Lee, Chun Gwon Park and Dong Keun Han*, Comparative Analysis of MSC-Derived Exosomes Depending on Cell Culture Media for Regenerative Bioactivity, Tissue Eng Regen Med. 2021 Jun;18(3):355-367.
  • Intan Rosalina Suhito, Novi Angeline, Kwang‐Ho Lee, Huijung Kim, Chun Gwon Park, Zhengtang Luo and Tae‐Hyung Kim*, A Spheroid‐Forming Hybrid Gold Nanostructure Platform That Electrochemically Detects Anticancer Effects of Curcumin in a Multicellular Brain Cancer Model, Small. 2021 Apr;17(15):e2002436.
  • Jun Yong Kim, Won-Kyu Rhim, Yong-In Yoo, Da-Seul Kim, Kyoung-Won Ko, Yun Heo, Chun Gwon Park and Dong Keun Han*, Defined MSC exosome with high yield and purity to improve regenerative activity, J Tissue Eng. 2021 Apr 20;12:20417314211008626.

These authors contributed equally to this work.

2020

  • Yehlin Cho, Junyoung Seo, Yeonbo Sim, Jinkyoung Chung, Chan E. Park, Chun Gwon Park, Doory Kim and Jae-Byum Chang*, FRACTAL: Signal amplification of immunofluorescence via cyclic staining of target molecules, Nanoscale. 2020 Dec 8;12(46):23506-23513.
  • Yun Young Lee, Hee Ho Park, Wooram Park, Hyelim Kim, Jong Geol Jang, Kyung Soo Hong, Jae-Young Lee, Hee Seung Seo, Dong Hee Na, Tae-Hyung Kim, Young Bin Choy, June Hong Ahn,*, Wonhwa Lee,* and Chun Gwon Park*, Long-acting Nanoparticulate DNase-1 for Effective Suppression of SARS-CoV-2-mediated Neutrophil Activities and Cytokine Storm, Biomaterials. 2021 Jan;267:120389.

These authors contributed equally to this work.

  • Hee Ho Park1, Wooram Park1Yun Young Lee1, Hyelim Kim, Hee Seung Seo, Dong Wook Choi, Ho-Keun Kwon, Dong Hee Na, Tae-Hyung Kim, Young Bin Choy, June Hong Ahn*, Wonhwa Lee* and Chun Gwon Park*, Bioinspired DNase-I-coated melanin-like nanospheres for modulation of infection-associated NETosis dysregulation, Adv Sci (Weinh). 2020 Oct 20;7(23):2001940.

1 These authors contributed equally to this work.

  • Wonhwa Lee1, June Hong Ahn1, Hee Ho Park1, Hong Nam Kim1, Hyelim Kim, Youngbum Yoo, Hyosoo Shin, Kyung Soo Hong, Jong Geol Jang, Chun Gwon Park, Eun Young Choi*, Jong-Sup Bae* and Young-Kyo Seo*, COVID-19-activated SREBP2 disturbs cholesterol biosynthesis and leads to cytokine storm, Signal Transduct Target Ther. 2020 Sep 3;5(1):186.

1 These authors contributed equally to this work.

  • Chun Gwon Park‡, Goeun Choi‡, Myung Hun Kim‡, Se-Na Kim, Hanna Lee, Na Kyeong Lee, Young Bin Choy* and Jin-Ho Choy*, Brimonidine–Montmorillonite Hybrid Formulation for Topical Drug Delivery to the Eye, J Mater Chem B. 2020 Sep 21;8(35):7914-7920.

‡ These authors contributed equally to this work.

  • Seyoung Hong, Dong Wook Choi, Hong Nam KimChun Gwon Park*, Wonhwa Lee* and Hee Ho Park*, Protein-Based Nanoparticles as Drug Delivery Systems, Pharmaceutics. 2020 Jun 29;12(7):604.

These authors contributed equally to this work.

  • Hyung Woo Park1Chun Gwon Park1, Min Park1, Seung Ho Lee, Hye Ran Park, Jaesung Lim, Sun Ha Paek* and Young Bin Choy*, Intrastriatal administration of coenzyme Q10 enhances neuroprotection in a Parkinson’s disease rat model, Sci Rep. 2020 Jun 12;10(1):9572.

1 These authors contributed equally to this work.

  • Wooram Park‡, Kwang Hoon Song‡, Jaesung LimChun Gwon Park, Junsang Doh* and Dong Keun Han*, Biomaterial-based strategies to prime dendritic cell-mediated anti-cancer immune responses , Int. Mater. Rev. 2020 Mar 18;65(7):445-462.

‡ These authors contributed equally to this work.

  • Novi Angeline, Intan Rosalina Suhito, Cheol-Hwi Kim, Geun-Pyo Hong, Chun Gwon Park, Suk Ho Bhang, Zhengtang Luo and Tae-Hyung Kim*, A fibronectin-coated gold nanostructure composite for electrochemical detection of effects of curcumin-carrying nanoliposomes on human stomach cancer cells, Analyst. 2020 Jan 21;145(2):675-684.

2019

  • Seung Ho Lee1, Huiyan Piao1, Yong Chan Cho, Se-Na Kim, Goeun Choi, Cho Rim Kim, Han Bi Ji, Chun Gwon Park, Cheol Lee, Chong In Shin, Won-Gun Koh, Young Bin Choy* and Jin-Ho Choy*, Implantable multireservoir device with stimulusresponsive membrane for on-demand and pulsatile delivery of growth hormone, Proc Natl Acad Sci U S A. 2019 Jun 11;116(24):11664-11672.

1 These authors contributed equally to this work.

2018

  • Jean Albrengues, Mario A. Shields, David Ng, Chun Gwon Park, Alexandra Ambrico, Morgan E. Poindexter, Priya Upadhyay, Dale L. Uyeminami, Arnaud Pommier, Victoria Küttner, Emilis Bružas, Laura Maiorino, Carmelita Bautista, Ellese M. Carmona, Phyllis A. Gimotty, Douglas T. Fearon, Kenneth Chang, Scott K. Lyons, Kent E. Pinkerton, Lloyd C. Trotman, Michael S. Goldberg, Johannes T.-H. Yeh and Mikala Egeblad*, Neutrophil extracellular traps produced during inflammation awaken dormant cancer cells in mice, Science. 2018 Sep 28;361(6409):eaao4227.
  • Se-Na KimChun Gwon Park, Beom Kang Huh, Seung Ho Lee, Chang Hee Min, Yun Young Lee, Young Kook Kim, Ki Ho Park and Young Bin Choy*, Metal-organic frameworks, NH2-MIL-88(Fe), as carriers for ophthalmic delivery of brimonidine, Acta Biomater. 2018 Oct 1;79:344-353.

These authors contributed equally to this work.

  • Chun Gwon Park, Christina A. Hartl, Daniela Schmid, Ellese M. Carmona, Hye-Jung Kim and Michael S. Goldberg*, Extended release of perioperative immunotherapy prevents tumor recurrence and eliminates metastases, Sci Transl Med. 2018 Mar 21;10(433):eaar1916.
  • Seung Ho Lee, Byung Hwi Kim, Chun Gwon Park, Cheol Lee, Byung Yoon Lim and Young Bin Choy*, Implantable small device enabled with magnetic actuation for on-demand and pulsatile drug delivery, J Control Release. 2018 Sep 28;286:224-230. 
  • Se-Na Kim, Song Ah KoChun Gwon Park, Seung Ho Lee, Beom Kang Huh, Yoh Han Park, Young Kook Kim, Ahnul Ha, Ki Ho Park, and Young Bin Choy*, Amino-Functionalized Mesoporous Silica Particles for Ocular Delivery of Brimonidine, Mol Pharm. 2018 Aug 6;15(8):3143-3152.

These authors contributed equally to this work.

  • Seung Ho Lee, Yong Chan Cho, Dong Yeon Nam, Beom Kang Huh, Se-Na Kim, Dong Hoon Lee, Chun Gwon Park and Young Bin Choy*, Designing Minimally Invasive Preocular Contact Tips for Potential Application in Tear Collection, Cornea. 2018 Sep;37(9):1163-1168.

These authors contributed equally to this work.

2017

  • Daniela SchmidChun Gwon Park, Christina A. Hartl, Nikita Subedi, Adam N. Cartwright, Regina Bou Puerto, Yiran Zheng, James Maiarana, Gordon J. Freeman, Kai W. Wucherpfennig, Darrell J. Irvine and Michael S. Goldberg*, T cell-targeting nanoparticles focus delivery of immunotherapy to improve antitumor immunity, Nat Commun. 2017 Nov 23;8(1):1747.

These authors contributed equally to this work.

  • Chun Gwon Park, Beom Kang Huh, Se-Na Kim, Seung Ho Lee, Hye Rim Hong and Young Bin Choy*, Nanostructured mucoadhesive microparticles to enhance oral drug bioavailability, Ind. Eng. Chem. Res. 2017 Oct 25;54:262-269.
  • Beom Kang Huh1, Byung Hwi Kim, Se-Na Kim1Chun Gwon Park, Seung Ho Lee, Ka Ryeong Kim, Chan Yeong Heo* and Young Bin Choy**, Surgical suture braided with a diclofenac-loaded strand of poly(lactic-co-glycolic acid) for local, sustained pain mitigation, Mater Sci Eng C Mater Biol Appl. 2017 Oct 1;79:209-215.

1 These authors contributed equally to this work.

  • Esther J. Lee1, Beom Kang Huh1, Se-Na Kim1, Jae Yeon Lee, Chun Gwon Park, Antonios G. Mikos* and Young Bin Choy*, Application of materials as medical devices with localized drug delivery capabilities for enhanced wound repair, Prog Mater Sci. 2017 Aug;89:392-410.

1 These authors contributed equally to this work.

  • Chun Gwon Park‡, Min Park‡, Byung Hwi Kim, Seung Ho Lee, Joong Yull Park, Ho Hyun Park, Kangwon Lee, Hyun-Kwang Seok and Young Bin Choy*, Pattern-Coated Titanium Bone Fixation Plate for Dual Delivery of Vancomycin and Alendronate, Macromol. Res. 2017 May 25:756-762.

‡ These authors contributed equally to this work.

  • Seung Ho Lee‡, Young Bin Lee‡, Byung Hwi Kim, Cheol Lee, Young Min Cho, Se-Na KimChun Gwon Park, Yong-Chan Cho and Young Bin Choy*, Implantable batteryless device for on-demand and pulsatile insulin administration, Nat Commun. 2017 Apr 13;8:15032.

‡ These authors contributed equally to this work.

  • Chun Gwon Park, Young Kook Kim, Se-Na Kim, Seung Ho Lee, Beom Kang Huh, Min-A Park, Hyein Won, Ki Ho Park and Young Bin Choy*, Enhanced ocular efficacy of topically-delivered dorzolamide with nanostructured mucoadhesive microparticles, Int J Pharm. 2017 Apr 30;522(1-2):66-73.
  • Byung Hwi Kim1, Min Park1, Hyo Jin Park, Seung Ho Lee, Sung Yoon Choi, Chun Gwon Park, Su Min Han, Chan Yeong Heo* and Young Bin Choy*, Prolonged, acute suppression of cysteinyl leukotriene to reduce capsular contracture around silicone implants, Acta Biomater. 2017 Mar 15;51:209-219.

1 These authors contributed equally to this work.

  • Mingyu Lee‡, Chun Gwon Park‡, Beom Kang Huh, Se-Na Kim, Seung Ho Lee, Roza Khalmuratova, Jong-Wan Park, Hyun-Woo Shin and Young Bin Choy*, Sinonasal Delivery of Resveratrol via Mucoadhesive Nanostructured Microparticles in a Nasal Polyp Mouse Model, Sci Rep. 2017 Jan 10;7:40249.

‡ These authors contributed equally to this work.

2016

  • Ik Sung Cho, Chun Gwon Park, Beom Kang Huh, Myeong Ok Cho, Zehedina Khatun, Zhengzheng Li, Sun-Woong Kang, Young Bin Choy* and Kang Moo Huh*, Thermosensitive hexanoyl glycol chitosan-based ocular delivery system for glaucoma therapy, Acta Biomater. 2016 Jul 15;39:124-132.
  • Chun Gwon Park1, Karam Choi1, Young Kook Kim, Ki Ho Park, Sungwan Kim* and Young Bin Choy**, Mathematical modelling of brimonidine absorption via topical delivery of microparticle formulations to the eye, J Ind Eng Chem. 2016 Jul 25;39:194-202.
  • Won Seok Lee, Min Park, Myung Hun Kim, Chun Gwon Park, Beom Kang Huh, Hyun Kwang Seok and Young Bin Choy*, Nanoparticle coating on the silane-modified surface of magnesium for local drug delivery and controlled corrosion, J Biomater Appl. 2016 Jan;30(6):651-61.
  • Woojune Hur1, Min Park1, Jae Yeon Lee, Myung Hun Kim, Seung Ho Lee, Chun Gwon Park, Se-Na Kim, Hye Sook Min, Hye Jeong Min, Jin Ho Chai, Sang Jeong Lee, Sukwha Kim, Tae Hyun Choi* and Young Bin Choy*, Bioabsorbable Bone Plates Enabled with Local, Sustained Delivery of Alendronate for Bone Regeneration, J Control Release. 2016 Jan 28;222:97-106.

1 These authors contributed equally to this work.

2015

  • Chul Whan Yoon1, Jae Hong Ahn1, Doh Park1, Jae Yeon Lee1Chun Gwon Park, Min Park and Young Bin Choy*, Studies on Osmotically Driven Drug Infusion Pump Under the Change in Body-Simulating Environment, Biomed. 2015 Dec 31;36(6):291-295.

1 These authors contributed equally to this work.

  • Chun Gwon Park, Young Kook Kim, Mi Jeung Kim, Min Park, Myung Hun Kim, Seung Ho Lee, Sung Yoon Choi, Won Seok Lee, You Jung Chung, Young Eun Jung, Ki Ho Park* and Young Bin Choy**, Mucoadhesive microparticles with a nanostructured surface for enhanced bioavailability of glaucoma drug, J Control Release. 2015 Dec 28;220(Pt A):180-188.
  • Chun Gwon Park†, Catherine Shasteen†, Zohreh Amoozgar†, Joonyoung Park, Se-Na Kim, Ji Eun Lee, Min Jae Lee, Yoorock Suh, Hyun Kwang Seok, Yoon Yeo* and Young Bin Choy**, Photo-Crosslinkable Chitosan Hydrogel as a Bioadhesive for Esophageal Stents, Macromol. Res. 2015 Sep 23(9):882-884.

† These authors contributed equally to this work.

  • Subin Park1, Min Park1, Byung Hwi Kim1, Ji Eun Lee, Hyo Jin Park, Seung Ho Lee, Chun Gwon Park, Myung Hun Kim, Ryul Kim, Eun Hee Kim, Chan Yeong Heo, Young Bin Choy*, Acute suppression of TGF-ß with local, sustained release of tranilast against the formation of fibrous capsules around silicone implants, J Control Release. 2015 Feb 28;200:125-37.

1 These authors contributed equally to this work.

  • Sung Yoon Choi1, Woojune Hur1, Byeung Kyu Kim1, Catherine Shasteen, Myung Hun Kim, La Mee Choi, Seung Ho Lee, Chun Gwon Park, Min Park, Hye Sook Min, Sukwha Kim, Tae Hyun Choi* and Young Bin Choy*, Bioabsorbable bone fixation plates for X‐ray imaging diagnosis by a radiopaque layer of barium sulfate and poly(lactic‐co‐glycolic acid), J Biomed Mater Res B Appl Biomater. 2015 Apr;103(3):596-607.

1 These authors contributed equally to this work.

2014

  • Seung Ho Lee, Min Park, Chun Gwon Park, Byung-Hwi Kim, Jieun Lee, Sung Yoon Choi, So-rae Nam, Sung-Hye Park, Young Bin Choy*, Implantable micro-chip for controlled delivery of diclofenac sodium, J Control Release. 2014 Dec 28;196:52-9.
  • Chun Gwon Park, Mi Jeung Kim, Min Park, Sung Yoon Choi, Seung Ho Lee, Ji Eun Lee, Gyeong-Seon Shin, Ki Ho Park and Young Bin Choy*, Nanostructured mucoadhesive microparticles for enhanced preocular retention, Acta Biomater. 2014 Jan;10(1):77-86.

2013

  • Ji Eun Lee1, Subin Park1, Min Park, Myung Hun Kim, Chun Gwon Park, Seung Ho Lee, Sung Yoon Choi, Byung Hwi Kim, Hyo Jin Park Ji-Ho Park, Chan Yeong Heo and Young Bin Choy*, Surgical suture assembled with polymeric drug-delivery sheet for sustained, local pain relief, Acta Biomater. 2013 Sep;9(9):8318-27.

1 These authors contributed equally to this work.

  • Min Park, Ji Eun Lee, Chun Gwon Park, Seung Ho Lee, Hyun Kwang Seok and Young Bin Choy*, Polycaprolactone coating with varying thicknesses for controlled corrosion of magnesium, J. Coat. Technol. Res. 2013 10 (5) 695–706.
  • Catherine Shasteen, Seok Min Kwon, Keun Yung Park, Sun Young Jung, Seung Ho Lee, Chun Gwon Park, Myung Hun Kim, Sukwha Kim, Woo-Chan Son, Tae Hyun Choi* and Young Bin Choy*, Biodegradable internal fixation plates enabled with X-ray visibility by a radiopaque layer of b-tricalcium phosphate and poly (lactic-co-glycolic acid), J Biomed Mater Res B Appl Biomater. 2013 Feb;101(2):320-9.

* Both authors contributed equally to this paper.

2012

  • Min Park, Chun Gwon Park, Seung Ho Lee, Ji Eun Lee, Eunbit Cho, Mark R. Prausnitz and Young Bin Choy*, Polymeric Tube-Shaped Devices with Controlled Geometry for Programmed Drug Delivery, Macromol. Res. 2012 20(9): 960-967.
  • Ji Eun Lee1Chun Gwon Park1, Byeong Moo An, Myung Hun Kim, Min Park, Seung Ho Lee and Young Bin Choy*, Linear Delivery of Verapamil via Nanofibrous Sheet-Based System, Pharm Res. 2012 Jul;29(7):1787-96.

1 These authors contributed equally to this work.

  • Seung Ho Lee, Min Park, Chun Gwon Park, Ji Eun Lee, Mark R. Prausnitz and Young Bin Choy*, Microchip for Sustained Drug Delivery by Diffusion Through Microchannels, AAPS PharmSciTech. 2012 Mar;13(1):211-7.

2011

  • Chun Gwon Park, Myung Hun Kim, Min Park, Ji Eun Lee, Seung Ho Lee, Jung-Hwan Park, Kyung-Hwan Yoon and Young Bin Choy*, Polymeric Nanofiber Coated Esophageal Stent for Sustained Delivery of an Anticancer Drug, Macromol. Res. 2011 Oct 01;19:1210.
  • Chun Gwon Park, Eunji Kim, Min Park, Jung-Hwan Park and Young Bin Choy*, A nanofibrous sheet-based system for linear delivery of nifedipine, J Control Release. 2011 Feb 10;149(3):250-7.